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The molecular basis, genetic control and pleiotropic effects of local gene co-expression

In this work, we investigate how local gene co-expression leads to pleiotropy and comorbidity and provide functional interpretation of QTL and GWAS findings.

High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs

We developed a scalable, high throughput approach to generate high fidelity low pass whole genome and HLA sequencing, viral genomes, and representation of human transcriptome from single nasopharyngeal swabs of COVID19 patients.