Simone Rubinacci

Simone Rubinacci

Postdoctoral researcher in Statistical Genomics

Department of Computational Biology, University of Lausanne, CH

About me

I am a postdoctoral researcher at the Systems and Population Genetics Group, University of Lausanne. My research is mainly focused in the development of statistical methods for genotype imputation and haplotype phasing.

I did my DPhil at the Department of Statistics of the University of Oxford, supervised by Jonathan Marchini and Pier Palamara and graduated in May 2020. During my DPhil I developed IMPUTE5, a software for genotype imputation of SNP array datasets.

More recently, me and colleagues of the Systems and Population Genetics Group released GLIMPSE, a fast and accurate method for imputing haplotypes and genotypes from low-coverage sequencing data.

In my free time I like to go hiking in the Swiss/Italian Alps or explore the neighbouring villages with my bike. When not in Switzerland, I am likely to be found in a quiet Finnish forest picking berries or in a sauna!

Download my resumé.

Interests
  • Genotype imputation
  • Population genetics
  • GWAS
Education
  • Phd in Statistical Genomics, 2020

    Department of Statistics, University of Oxford, UK

  • Msc in Computer Science, 2014

    Department of Computer Science, University of Milano-Bicocca, IT

  • Research Assistant, 2014

    Department of Computer Science, University of Oxford, UK

Experience

 
 
 
 
 
Postdoctoral researcher
Nov 2019 – Present Lausanne, Switzerland

Main research topics:

  • Genotype imputation
  • Haplotype phasing
 
 
 
 
 
Dphil student
Oct 2015 – May 2020 Oxford, United Kingdom
Dphil in Statistical Genomics.
 
 
 
 
 
Research Assistant
Mar 2015 – Sep 2015 Milan, Italy
Research assistant in the ‘Bioinformatics Milano-Bicocca’ (BIMIB) group, led by Professor Marco Antoniotti.
 
 
 
 
 
Junior Research Assistant
Jan 2014 – Aug 2014 Oxford, United Kingdom
Junior research assistant in the ‘Computational Biology’ group, led by Professor David Gavaghan.
 
 
 
 
 
MSc student
Oct 2012 – Mar 2015 Milan, Italy
MSc in Computer Science.

Awards

EXTRA award (master students)
Research funding for master’s thesis project at the Department of Computer Science, University of Oxford, UK

Recent & Upcoming Talks

Talk @EMGM2021!
Evaluation of low-coverage whole genome sequencing imputation across human populations
Seminar at University of Bern
Next-generation genotype imputation methods

Other publications

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(2020). The molecular basis, genetic control and pleiotropic effects of local gene co-expression. In BiorXiv.

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(2019). TISCO: Temporal scoping of facts. In Journal of Web Semantics.

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(2015). CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer. In Cancer Informatics.

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